Anti-MSI1 antibody (1-100) [S5MR] (STJ11102425)

Name: Anti-MSI1 antibody (1-100) [S5MR] (STJ11102425)
SKU: STJ11102425
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⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityMonoclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ11102425

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Short Description	Rabbit monoclonal Musashi 1/Msi1 (1-100) antibody for use in WB, IF, ICC and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/IF/ICC/ELISA
Host	Rabbit
Reactivity	Human/Mouse
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Monoclonal
Clone ID	S5MR
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:500-1:2000 IF/ICC:1:50-1:200 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	MSI1
Gene ID	4440
Uniprot ID	MSI1H_HUMAN
Immunogen Region	1-100
Immunogen Sequence	METDAPQPGLASPDSPHDPC KMFIGGLSWQTTQEGLREYF GQFGEVKECLVMRDPLTKRS RGFGFVTFMDQAGVDKVLAQ SRHELDSKTIDPKVAFPRRA
Specificity	A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MSI1 (O43347).

Tissue Specificity	Detected in fetal kidney, brain, liver and lung, and in adult brain and pancreas. Detected in hepatoma cell lines.
Function	RNA binding protein that regulates the expression of target mRNAs at the translation level. Regulates expression of the NOTCH1 antagonist NUMB. Binds RNA containing the sequence 5'-GUUAGUUAGUUAGUU-3' and other sequences containing the pattern 5'-GAU(1-3)AGU-3'. May play a role in the proliferation and maintenance of stem cells in the central nervous system.
Protein Name	Rna-Binding Protein Musashi Homolog 1 Musashi-1
Database Links	Reactome: R-HSA-9010553
Cellular Localisation	Cytoplasm Nucleus
Alternative Antibody Names	Anti-Rna-Binding Protein Musashi Homolog 1 antibody Anti-Musashi-1 antibody Anti-MSI1 antibody

Information sourced from Uniprot.org