Host: | Rabbit |
Applications: | WB/IF |
Reactivity: | Human/Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit monoclonal antibody anti-Musashi 1/Msi1 (1-100) is suitable for use in Western Blot and Immunofluorescence research applications. |
Clonality: | Monoclonal |
Clone ID: | S5MR |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3. |
Purification: | Affinity purification |
Dilution Range: | WB 1:500-1:2000 IF/ICC 1:50-1:200 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | MSI1 |
Gene ID: | 4440 |
Uniprot ID: | MSI1H_HUMAN |
Immunogen Region: | 1-100 |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MSI1 (O43347). |
Immunogen Sequence: | METDAPQPGLASPDSPHDPC KMFIGGLSWQTTQEGLREYF GQFGEVKECLVMRDPLTKRS RGFGFVTFMDQAGVDKVLAQ SRHELDSKTIDPKVAFPRRA |
Tissue Specificity | Detected in fetal kidney, brain, liver and lung, and in adult brain and pancreas. Detected in hepatoma cell lines. |
Function | RNA binding protein that regulates the expression of target mRNAs at the translation level. Regulates expression of the NOTCH1 antagonist NUMB. Binds RNA containing the sequence 5'-GUUAGUUAGUUAGUU-3' and other sequences containing the pattern 5'-GAU(1-3)AGU-3'. May play a role in the proliferation and maintenance of stem cells in the central nervous system. |
Protein Name | Rna-Binding Protein Musashi Homolog 1 Musashi-1 |
Database Links | Reactome: R-HSA-9010553 |
Cellular Localisation | Cytoplasm Nucleus |
Alternative Antibody Names | Anti-Rna-Binding Protein Musashi Homolog 1 antibody Anti-Musashi-1 antibody Anti-MSI1 antibody |
Information sourced from Uniprot.org