Host: | Mouse |
Applications: | IHC/WB/IF |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Mouse monoclonal antibody anti-B-lymphocyte antigen CD20 (100-200 aa) is suitable for use in Immunohistochemistry, Western Blot and Immunofluorescence research applications. |
Clonality : | Monoclonal |
Clone ID : | ABT292 |
Conjugation: | Unconjugated |
Isotype: | IgG1k |
Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
Dilution Range: | IHC-P 1:100-500WB 1:200-1000IF 1:100-500 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | MS4A1 |
Gene ID: | 931 |
Uniprot ID: | CD20_HUMAN |
Immunogen Region: | 100-200 aa |
Specificity: | The antibody can specifically recognize human CD20 protein. |
Immunogen: | Synthesized peptide derived from the human CD20 at the amino acid range 100-200 |
Post Translational Modifications | Phosphorylated on serines and threonines in resting B-cells. Protein kinase C/PKC can use CD20 as substrate. |
Function | B-lymphocyte-specific membrane protein that plays a role in the regulation of cellular calcium influx necessary for the development, differentiation, and activation of B-lymphocytes. Functions as a store-operated calcium (SOC) channel component promoting calcium influx after activation by the B-cell receptor/BCR. |
Protein Name | B-Lymphocyte Antigen Cd20B-Lymphocyte Surface Antigen B1Bp35Leukocyte Surface Antigen Leu-16Membrane-Spanning 4-Domains Subfamily A Member 1Cd Antigen Cd20 |
Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinLipid-AnchorConstitutively Associated With Membrane Rafts |
Alternative Antibody Names | Anti-B-Lymphocyte Antigen Cd20 antibodyAnti-B-Lymphocyte Surface Antigen B1 antibodyAnti-Bp35 antibodyAnti-Leukocyte Surface Antigen Leu-16 antibodyAnti-Membrane-Spanning 4-Domains Subfamily A Member 1 antibodyAnti-Cd Antigen Cd20 antibodyAnti-MS4A1 antibodyAnti-CD20 antibody |
Information sourced from Uniprot.org