Anti-MRRF antibody (163-262) [S3MR] (STJ11103493)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal MRRF (163-262) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | S3MR |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MRRF |
| Gene ID | 92399 |
| Uniprot ID | RRFM_HUMAN |
| Immunogen Region | 163-262 |
| Immunogen Sequence | RESGMNLNPEVEGTLIRVPI PQVTREHREMLVKLAKQNTN KAKDSLRKVRTNSMNKLKKS KDTVSEDTIRLIEKQISQMA DDTVAELDRHLAVKTKELLG |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 163-262 of human MRRF (Q96E11). |
Additional Info
| Function | Responsible for the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with GFM2. Promotes mitochondrial ribosome recycling by dissolution of intersubunit contacts. |
| Protein Name | Ribosome-Recycling Factor - MitochondrialRrfMtrrfRibosome-Releasing Factor - Mitochondrial |
| Database Links | Reactome: R-HSA-5419276 |
| Cellular Localisation | Mitochondrion |
| Alternative Antibody Names | Anti-Ribosome-Recycling Factor - Mitochondrial antibodyAnti-Rrf antibodyAnti-Mtrrf antibodyAnti-Ribosome-Releasing Factor - Mitochondrial antibodyAnti-MRRF antibody |
Information sourced from Uniprot.org