| Post Translational Modifications | MRPL32 precursor is processed by the m-AAA protease (composed of AFG3L2 and SPG7), which cleaves the N-terminal transit peptide. Cleavage by the m-AAA protease takes place prior to assembly into the large subunit, an essential step for mitochondrial ribosome (mitoribosome) assembly. Proper processing by the m-AAA protease is dependent on the zinc-binding region within the tightly folded C-terminal domain of MRPL32: zinc-dependent folding halts degradation initiated from the N-terminus and triggers the release of mature MRPL32. |
| Function | Component of the mitochondrial large ribosomal subunit (mt-LSU). The mitochondrial ribosome (mitoribosome) is a large ribonucleoprotein complex responsible for the synthesis of proteins inside mitochondria. |
| Protein Name | Large Ribosomal Subunit Protein Bl32m39s Ribosomal Protein L32 - MitochondrialL32mtMrp-L32 |
| Database Links | Reactome: R-HSA-5368286Reactome: R-HSA-5389840Reactome: R-HSA-5419276Reactome: R-HSA-9837999 |
| Cellular Localisation | Mitochondrion |
| Alternative Antibody Names | Anti-Large Ribosomal Subunit Protein Bl32m antibodyAnti-39s Ribosomal Protein L32 - Mitochondrial antibodyAnti-L32mt antibodyAnti-Mrp-L32 antibodyAnti-MRPL32 antibodyAnti-HSPC283 antibody |
Information sourced from Uniprot.org
