Tissue Specificity | Uniquely localized in a subset of small dorsal root and trigeminal sensory neurons. Associated preferentially with IB4 class of small-diameter somatosensory afferents (also known as nociceptors). |
Function | Orphan receptor activated by neuropeptides terminating in Arg-Phe or Arg-Phe-amide. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. May regulate the function of nociceptive neurons by modulation of pain perception. |
Protein Name | Mas-Related G-Protein Coupled Receptor Member X1Sensory Neuron-Specific G-Protein Coupled Receptor 1 |
Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
Alternative Antibody Names | Anti-Mas-Related G-Protein Coupled Receptor Member X1 antibodyAnti-Sensory Neuron-Specific G-Protein Coupled Receptor 1 antibodyAnti-Mrgprx1 antibodyAnti-Mrgc antibodyAnti-Mrgprc antibodyAnti-Mrgprc11 antibodyAnti-Snsr antibodyAnti-Snsr1 antibody |
Information sourced from Uniprot.org