Immunofluorescence analysis of paraffin-embedded Human lung tissue using MRC1/CD206 Rabbit polyclonal antibody (STJ11105645) at a dilution of 1:50 (40x lens). Secondary antibody:Cy3 Goat Anti-Rabbit IgG (H+L) at 1:500 dilution. Blue: DAPI for nuclear staining. Perform high pressure antigen retrieval with 0. 01 M citrate buffer (pH 6. 0) prior to IF staining.

Anti-MRC1 antibody (19-1389) (STJ11105645)

SKU:
STJ11105645
$151.88 - $708.08
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Host: Rabbit
Applications: WB/IF/ICC/ELISA
Reactivity: Human/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:1000
IF/ICC:1:50-1:200
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: MRC1
Gene ID: 4360
Uniprot ID: MRC1_HUMAN
Immunogen Region: 19-1389
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 19-1389 of human Mannose Receptor/CD206 (NP_002429.1).
Immunogen Sequence: LDTRQFLIYNEDHKRCVDAV SPSAVQTAACNQDAESQKFR WVSESQIMSVAFKLCLGVPS KTDWVAITLYACDSKSEFQK WECKNDTLLGIKGEDLFFNY GNRQEKNIMLYKGSGLWSRW KIYGTTDNLCSRGYEAMYTL LGNANGATCAFPFKFENKWY ADCTSAGRSDGWLWCGTTTD YDTDKLFGYCPLKFEGSESL WNKDPLTSVSYQINSKSALT WHQARKSCQQQNAELLSIT
Function Mediates the endocytosis of glycoproteins by macrophages. Binds both sulfated and non-sulfated polysaccharide chains. (Microbial infection) Acts as a phagocytic receptor for bacteria, fungi and other pathogens. (Microbial infection) Acts as a receptor for Dengue virus envelope protein E. (Microbial infection) Interacts with Hepatitis B virus envelope protein.
Protein Name Macrophage Mannose Receptor 1
Mmr
C-Type Lectin Domain Family 13 Member D
C-Type Lectin Domain Family 13 Member D-Like
Human Mannose Receptor
Hmr
Macrophage Mannose Receptor 1-Like Protein 1
Cd Antigen Cd206
Database Links Reactome: R-HSA-1236978
Reactome: R-HSA-9637628
Cellular Localisation Endosome Membrane
Single-Pass Type I Membrane Protein
Cell Membrane
Alternative Antibody Names Anti-Macrophage Mannose Receptor 1 antibody
Anti-Mmr antibody
Anti-C-Type Lectin Domain Family 13 Member D antibody
Anti-C-Type Lectin Domain Family 13 Member D-Like antibody
Anti-Human Mannose Receptor antibody
Anti-Hmr antibody
Anti-Macrophage Mannose Receptor 1-Like Protein 1 antibody
Anti-Cd Antigen Cd206 antibody
Anti-MRC1 antibody
Anti-CLEC13D antibody
Anti-CLEC13DL antibody
Anti-MRC1L1 antibody

Information sourced from Uniprot.org

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