| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | S4607RM |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:2000-1:20000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MPZ |
| Gene ID: | 4359 |
| Uniprot ID: | MYP0_HUMAN |
| Immunogen Region: | 149-248 |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 149-248 of human Myelin Protein Zero (MPZ) (NP_000521.2). |
| Immunogen Sequence: | KVPTRYGVVLGAVIGGVLGV VLLLLLLFYVVRYCWLRRQA ALQRRLSAMEKGKLHKPGKD ASKRGRQTPVLYAMLDHSRS TKAVSEKKAKGLGESRKDKK |
| Tissue Specificity | Found only in peripheral nervous system Schwann cells. |
| Post Translational Modifications | N-glycosylated.contains sulfate-substituted glycan. |
| Function | Is an adhesion molecule necessary for normal myelination in the peripheral nervous system. It mediates adhesion between adjacent myelin wraps and ultimately drives myelin compaction. |
| Protein Name | Myelin Protein P0Myelin Peripheral ProteinMppMyelin Protein Zero |
| Database Links | Reactome: R-HSA-9619665 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinIsoform L-Mpz: Myelin Membrane |
| Alternative Antibody Names | Anti-Myelin Protein P0 antibodyAnti-Myelin Peripheral Protein antibodyAnti-Mpp antibodyAnti-Myelin Protein Zero antibodyAnti-MPZ antibody |
Information sourced from Uniprot.org