| Tissue Specificity | Expressed in retina (at protein level) at the subapical region (SAR) adjacent to adherens junctions at the OLM, and at the OPL. |
| Function | Participates in cell spreading through the phosphoinositide-3-kinase (PI3K) pathway by connecting CADM1 to DLG1 and the regulatory subunit of phosphoinositide-3-kinase (PI3K). Stabilizes HTR2C at the plasma membrane and prevents its desensitization. May participates in the maintenance of adherens junctions. |
| Protein Name | Maguk P55 Subfamily Member 3Discs Large Homolog 3Protein Mpp3 |
| Cellular Localisation | Cell MembraneApical Cell MembraneCell JunctionAdherens JunctionLocalized In Apical Villi Of Mueller Glia CellsLocalized At The Apical Membrane In The Developing Cortex And Colocalized With Apical Proteins And Adherens Junction ProteinsLocalized At The Outer Limiting Membrane (Olm)And Outer Plexiform (Opl) Of Retina |
| Alternative Antibody Names | Anti-Maguk P55 Subfamily Member 3 antibodyAnti-Discs Large Homolog 3 antibodyAnti-Protein Mpp3 antibodyAnti-MPP3 antibodyAnti-DLG3 antibody |
Information sourced from Uniprot.org
