| Host: | Rabbit |
| Applications: | IHC/WB |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-MPP1 (10-60 aa) is suitable for use in Immunohistochemistry and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Lyophilised |
| Purification: | IgG purified |
| Dilution Range: | IHC, WB. A dilution of 1: 300 to 1: 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Storage Instruction: | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
| Gene Symbol: | MPP1 |
| Gene ID: | 4354 |
| Uniprot ID: | EM55_HUMAN |
| Immunogen Region: | 10-60 aa |
| Specificity: | Specific for MPP1. |
| Immunogen: | A synthetic peptide from aa region 10-60 of human MPP1 conjugated to an immunogenic carrier protein was used as the antigen. |
| Post Translational Modifications | Palmitoylated. |
| Function | Essential regulator of neutrophil polarity. Regulates neutrophil polarization by regulating AKT1 phosphorylation through a mechanism that is independent of PIK3CG activity. |
| Protein Name | 55 Kda Erythrocyte Membrane ProteinP55Membrane Protein - Palmitoylated 1 |
| Database Links | Reactome: R-HSA-9662361 |
| Cellular Localisation | Cell MembraneLipid-AnchorCell ProjectionStereociliumColocalizes With Whrn At Stereocilium Tip During Hair Cell DevelopmentColocalizes With Pals1 In The RetinaAt The Outer Limiting Membrane (Olm)Colocalizes With Whrn In The RetinaOuter Plexifirm Layer (Opl)Basal Bodies And At The Connecting Cilium (Cc)Colocalizes With Nf2 In Non-Myelin-Forming Schwann Cells |
| Alternative Antibody Names | Anti-55 Kda Erythrocyte Membrane Protein antibodyAnti-P55 antibodyAnti-Membrane Protein - Palmitoylated 1 antibodyAnti-MPP1 antibodyAnti-DXS552E antibodyAnti-EMP55 antibody |
Information sourced from Uniprot.org