• Immunofluorescence analysis of mouse bone marrow using Myeloperoxidase (MPO) Rabbit polyclonal antibody (STJ111084) at dilution of 1:100 (40x lens). Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) at 1:500 dilution. Blue: DAPI for nuclear staining.
  • Immunofluorescence analysis of rat bone marrow using Myeloperoxidase (MPO) Rabbit polyclonal antibody (STJ111084) at dilution of 1:100 (40x lens). Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) at 1:500 dilution. Blue: DAPI for nuclear staining.

Anti-MPO antibody (606-745) (STJ111084)

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STJ111084

£112.50 - £522.50
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Host: Rabbit
Applications: WB/IF
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-MPO (606-745) is suitable for use in Western Blot and Immunofluorescence research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.05% Proclin300, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
IF/ICC 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: MPO
Gene ID: 4353
Uniprot ID: PERM_HUMAN
Immunogen Region: 606-745
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 606-745 of human Myeloperoxidase (MPO) (NP_000241.1).
Immunogen Sequence: CGLPQPETVGQLGTVLRNLK LARKLMEQYGTPNNIDIWMG GVSEPLKRKGRVGPLLACII GTQFRKLRDGDRFWWENEGV FSMQQRQALAQISLPRIICD NTGITTVSKNNIFMSNSYPR DFVNCSTLPALNLASWREAS
Function Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity. Mediates the proteolytic cleavage of alpha-1-microglobulin to form t-alpha-1-microglobulin, which potently inhibits oxidation of low-density lipoprotein particles and limits vascular damage.
Protein Name Myeloperoxidase
Mpo Cleaved Into - Myeloperoxidase - 89 Kda Myeloperoxidase - 84 Kda Myeloperoxidase - Myeloperoxidase Light Chain - Myeloperoxidase Heavy Chain
Database Links Reactome: R-HSA-6798695
Reactome: R-HSA-8941413
Cellular Localisation Lysosome
Alternative Antibody Names Anti-Myeloperoxidase antibody
Anti-Mpo Cleaved Into - Myeloperoxidase - 89 Kda Myeloperoxidase - 84 Kda Myeloperoxidase - Myeloperoxidase Light Chain - Myeloperoxidase Heavy Chain antibody
Anti-MPO antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance