| Short Description : | Goat polyclonal antibody anti-Monoglyceride Lipase (Internal) is suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunofluorescence and Flow Cytometry research applications. |
| Applications: | Pep-ELISA/WB/IHC/IF/FC |
| Host: | Goat |
| Reactivity: | Human/Mouse/Rat/Dog/Cow |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 0.5 mg/mL |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:128000.WB: Approx 35kDa band observed in Mouse Adipose lysates and in preliminary testing of Human, Cerebellum lysate and in lysate of cell line NIH3T3 (calculated MW of 33.3kDa according to NP_ |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | MGLL |
| Gene ID: | 11343 |
| Uniprot ID: | MGLL_HUMAN |
| Accession Number: | NP_009214.1; NP_001003794.1 |
| Immunogen Region: | Internal |
| Immunogen Sequence: | QDLPHLVNADGQY |
| Specificity: | This antibody is expected to recognize both reported isoforms (NP_009214.1; NP_001003794.1). |
| Function | Converts monoacylglycerides to free fatty acids and glycerol. Hydrolyzes the endocannabinoid 2-arachidonoylglycerol, and thereby contributes to the regulation of endocannabinoid signaling, nociperception and perception of pain. Regulates the levels of fatty acids that serve as signaling molecules and promote cancer cell migration, invasion and tumor growth. |
| Protein Name | Monoglyceride LipaseMglHu-K5Lysophospholipase HomologLysophospholipase-LikeMonoacylglycerol LipaseMagl |
| Database Links | Reactome: R-HSA-1482883Reactome: R-HSA-163560Reactome: R-HSA-426048 |
| Cellular Localisation | CytoplasmCytosolMembranePeripheral Membrane Protein |
| Alternative Antibody Names | Anti-Monoglyceride Lipase antibodyAnti-Mgl antibodyAnti-Hu-K5 antibodyAnti-Lysophospholipase Homolog antibodyAnti-Lysophospholipase-Like antibodyAnti-Monoacylglycerol Lipase antibodyAnti-Magl antibodyAnti-MGLL antibody |
Information sourced from Uniprot.org
