| Host: | Mouse |
| Applications: | WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal anti-Mono-Methyl-Histone H1.1 and Histone H1.2 and Histone H1.3 and Histone H1.4-Lys25 for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Monoclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS pH7.4, 0.5% BSA, 0.02% Sodium Azide and 50% Glycerol. |
| Purification: | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
| Dilution Range: | WB 1:500-1000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | H1-4H1-2300830063007H14_HUMANH12_HUMANH13_HUMAN< |
| Specificity: | The antibody detects endogenous Histone H1 (Mono Methyl Lys25) protein. |
| Immunogen: | Synthetic Peptide of Histone H1 (Mono Methyl Lys25) |
| Function | Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation. |
| Protein Name | Histone H1.1Histone H1a |
| Database Links | Reactome: R-HSA-140342Reactome: R-HSA-2559584 |
| Cellular Localisation | NucleusChromosomeMainly Localizes In Euchromatin |
| Alternative Antibody Names | Anti-Histone H1.1 antibodyAnti-Histone H1a antibodyAnti-H1-1 antibodyAnti-H1F1 antibodyAnti-HIST1H1A antibody |
Information sourced from Uniprot.org
