| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MOGS |
| Gene ID: | 7841 |
| Uniprot ID: | MOGS_HUMAN |
| Immunogen Region: | 60-320 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 60-320 of human MOGS (NP_006293.2). |
| Immunogen Sequence: | RWVLAWYRARRAVTLHSAPP VLPADSSSPAVAPDLFWGTY RPHVYFGMKTRSPKPLLTGL MWAQQGTTPGTPKLRHTCEQ GDGVGPYGWEFHDGLSFGRQ HIQDGALRLTTEFVKRPGGQ HGGDWSWRVTVEPQDSGTSA LPLVSLFFYVVTDGKEVLLP EVGAKGQLKFISGHTSELGD FRFTLLPPTSPGDTAPKYGS YNVFWTSNPGLPLLTEMVKS RLNSWFQHRPPGAPPERYL |
| Function | In the context of N-glycan degradation, cleaves the distal alpha 1,2-linked glucose residue from the Glc(3)Man(9)GlcNAc(2) oligosaccharide precursor in a highly specific manner. |
| Protein Name | Mannosyl-Oligosaccharide Glucosidase Processing A-Glucosidase I |
| Database Links | Reactome: R-HSA-4793954 Reactome: R-HSA-532668 Reactome: R-HSA-9683686 Reactome: R-HSA-9694548 |
| Cellular Localisation | Endoplasmic Reticulum Membrane Single-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-Mannosyl-Oligosaccharide Glucosidase antibody Anti-Processing A-Glucosidase I antibody Anti-MOGS antibody Anti-GCS1 antibody |
Information sourced from Uniprot.org