| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-MNS1 (366-495) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
MNS1 |
| Gene ID: |
55329 |
| Uniprot ID: |
MNS1_HUMAN |
| Immunogen Region: |
366-495 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 366-495 of human MNS1 (NP_060835.1). |
| Immunogen Sequence: |
QAAKEEEENFRKTMLAKFAE DDRIELMNAQKQRMKQLEHR RAVEKLIEERRQQFLADKQR ELEEWQLQQRRQGFINAIIE EERLKLLKEHATNLLGYLPK GVFKKEDDIDLLGEEFRKVY QQRSEICEEK |
| Tissue Specificity | Expressed in nasal respiratory epithelium and in the sperm. |
| Function | Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating. May play a role in the control of meiotic division and germ cell differentiation through regulation of pairing and recombination during meiosis. Required for sperm flagella assembly. May play a role in the assembly and function of the outer dynein arm-docking complex (ODA-DC). ODA-DC mediates outer dynein arms (ODA) binding onto the axonemal doublet microtubules. |
| Protein Name | Meiosis-Specific Nuclear Structural Protein 1 |
| Cellular Localisation | NucleusCytoplasmCytoskeletonCilium AxonemeFlagellum AxonemeMicrotubule Inner Protein (Mip) Part Of The Dynein-Decorated Doublet Microtubules (Dmts) In Cilia Axoneme |
| Alternative Antibody Names | Anti-Meiosis-Specific Nuclear Structural Protein 1 antibodyAnti-MNS1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
