Anti-MN1 antibody (821-870) (STJ94167)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from human MN1. AA range:821-870
General Information
| Short Description | Rabbit polyclonal anti-Transcriptional activator MN1 (821-870) for use in WB, ELISA and IHC in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA/IHC |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000IHC-p 1:50-300ELISA 2000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MN1 |
| Gene ID | 4330 |
| Uniprot ID | MN1_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from human MN1. AA range:821-870 |
| Immunogen Region | 821-870 |
| Specificity | MN1 Polyclonal Antibody detects endogenous levels of MN1 protein. |
Additional Info
| Tissue Specificity | Widely expressed in fetal and adult tissues. Highest expression is observed in fetal brain and skeletal muscle, and adult skeletal muscle. |
| Function | Transcriptional activator which specifically regulates expression of TBX22 in the posterior region of the developing palate. Required during later stages of palate development for growth and medial fusion of the palatal shelves. Promotes maturation and normal function of calvarial osteoblasts, including expression of the osteoclastogenic cytokine TNFSF11/RANKL. Necessary for normal development of the membranous bones of the skull. May play a role in tumor suppression (Probable). |
| Protein Name | Transcriptional Activator Mn1Probable Tumor Suppressor Protein Mn1 |
| Database Links | |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Transcriptional Activator Mn1 antibodyAnti-Probable Tumor Suppressor Protein Mn1 antibodyAnti-MN1 antibody |
Information sourced from Uniprot.org