| Host: | Rabbit |
| Applications: | WB/IHC |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Matrix metalloproteinase-15 (611-660) is suitable for use in Western Blot and Immunohistochemistry research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000IHC-p 1:50-300 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MMP15 |
| Gene ID: | 4324 |
| Uniprot ID: | MMP15_HUMAN |
| Immunogen Region: | 611-660 |
| Specificity: | MMP-15 Polyclonal Antibody detects endogenous levels of MMP-15 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human MMP-15. AA range:611-660 |
| Tissue Specificity | Appeared to be synthesized preferentially in liver, placenta, testis, colon and intestine. Substantial amounts are also detected in pancreas, kidney, lung, heart and skeletal muscle. |
| Post Translational Modifications | The precursor is cleaved by a furin endopeptidase. |
| Function | Endopeptidase that degrades various components of the extracellular matrix. May activate progelatinase A. |
| Protein Name | Matrix Metalloproteinase-15Mmp-15Membrane-Type Matrix Metalloproteinase 2Mt-Mmp 2Mtmmp2Membrane-Type-2 Matrix MetalloproteinaseMt2-MmpMt2mmpSmcp-2 |
| Database Links | Reactome: R-HSA-1442490Reactome: R-HSA-1474228Reactome: R-HSA-1592389 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane ProteinExtracellular Side |
| Alternative Antibody Names | Anti-Matrix Metalloproteinase-15 antibodyAnti-Mmp-15 antibodyAnti-Membrane-Type Matrix Metalloproteinase 2 antibodyAnti-Mt-Mmp 2 antibodyAnti-Mtmmp2 antibodyAnti-Membrane-Type-2 Matrix Metalloproteinase antibodyAnti-Mt2-Mmp antibodyAnti-Mt2mmp antibodyAnti-Smcp-2 antibodyAnti-MMP15 antibody |
Information sourced from Uniprot.org