Anti-MMP15 antibody (611-660) (STJ94276)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from human MMP-15. AA range:611-660
General Information
| Short Description | Rabbit polyclonal anti-Matrix metalloproteinase-15 (611-660) for use in WB and IHC in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000IHC-p 1:50-300 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MMP15 |
| Gene ID | 4324 |
| Uniprot ID | MMP15_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from human MMP-15. AA range:611-660 |
| Immunogen Region | 611-660 |
| Specificity | MMP-15 Polyclonal Antibody detects endogenous levels of MMP-15 protein. |
Additional Info
| Tissue Specificity | Appeared to be synthesized preferentially in liver, placenta, testis, colon and intestine. Substantial amounts are also detected in pancreas, kidney, lung, heart and skeletal muscle. |
| Post Translational Modifications | The precursor is cleaved by a furin endopeptidase. |
| Function | Endopeptidase that degrades various components of the extracellular matrix. May activate progelatinase A. |
| Protein Name | Matrix Metalloproteinase-15Mmp-15Membrane-Type Matrix Metalloproteinase 2Mt-Mmp 2Mtmmp2Membrane-Type-2 Matrix MetalloproteinaseMt2-MmpMt2mmpSmcp-2 |
| Database Links | Reactome: R-HSA-1442490Reactome: R-HSA-1474228Reactome: R-HSA-1592389 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane ProteinExtracellular Side |
| Alternative Antibody Names | Anti-Matrix Metalloproteinase-15 antibodyAnti-Mmp-15 antibodyAnti-Membrane-Type Matrix Metalloproteinase 2 antibodyAnti-Mt-Mmp 2 antibodyAnti-Mtmmp2 antibodyAnti-Membrane-Type-2 Matrix Metalloproteinase antibodyAnti-Mt2-Mmp antibodyAnti-Mt2mmp antibodyAnti-Smcp-2 antibodyAnti-MMP15 antibody |
Information sourced from Uniprot.org