Anti-MMP12 nanobody [SAA1293] (STJN000213)

SPECIFICATIONS
ClonalityMonoclonal
HostAlpaca
ConjugationUnconjugated
IsotypeVHH-8His-Cys-tag
STJN000213
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General Information

Short DescriptionAlpaca monoclonal nanobody anti-Macrophage Metalloelastase is suitable for use in ELISA research applications.
ApplicationsELISA
HostAlpaca
ReactivityHuman
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityMonoclonal
Clone IDSAA1293
IsotypeVHH-8His-Cys-tag
ConjugationUnconjugated
Concentration1 mg/mL
PurificationPurified by Nickel column.
Formulation0.01M PBS, pH 7.4.
Storage InstructionUse a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at-20°C 12 months. Store at-80°C long term.

Target Information

Gene SymbolMMP12
Gene ID4321
Uniprot IDMMP12_HUMAN

Additional Info

Function May be involved in tissue injury and remodeling. Has significant elastolytic activity. Can accept large and small amino acids at the P1' site, but has a preference for leucine. Aromatic or hydrophobic residues are preferred at the P1 site, with small hydrophobic residues (preferably alanine) occupying P3.
Protein Name Macrophage Metalloelastase
Mme
Macrophage Elastase
Me
Hme
Matrix Metalloproteinase-12
Mmp-12
Database Links Reactome: R-HSA-1442490
Reactome: R-HSA-1474228
Cellular Localisation Secreted
Extracellular Space
Extracellular Matrix
Alternative Nanobody Names Anti-Macrophage Metalloelastase nanobody
Anti-Mme nanobody
Anti-Macrophage Elastase nanobody
Anti-Me nanobody
Anti-Hme nanobody
Anti-Matrix Metalloproteinase-12 nanobody
Anti-Mmp-12 nanobody
Anti-MMP12 nanobody
Anti-HME nanobody

Information sourced from Uniprot.org

Citations

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