Function | May be involved in tissue injury and remodeling. Has significant elastolytic activity. Can accept large and small amino acids at the P1' site, but has a preference for leucine. Aromatic or hydrophobic residues are preferred at the P1 site, with small hydrophobic residues (preferably alanine) occupying P3. |
Protein Name | Macrophage MetalloelastaseMmeMacrophage ElastaseMeHmeMatrix Metalloproteinase-12Mmp-12 |
Database Links | Reactome: R-HSA-1442490Reactome: R-HSA-1474228 |
Cellular Localisation | SecretedExtracellular SpaceExtracellular Matrix |
Alternative Nanobody Names | Anti-Macrophage Metalloelastase nanobodyAnti-Mme nanobodyAnti-Macrophage Elastase nanobodyAnti-Me nanobodyAnti-Hme nanobodyAnti-Matrix Metalloproteinase-12 nanobodyAnti-Mmp-12 nanobodyAnti-MMP12 nanobodyAnti-HME nanobody |
Information sourced from Uniprot.org