Anti-MLX antibody (Internal) (STJ72100)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-MLX (Internal) is suitable for use in ELISA and Immunohistochemistry research applications. |
| Applications | Pep-ELISA/IHC |
| Host | Goat |
| Reactivity | Human/Mouse/Rat/Dog/Cow |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:128000.WB: Preliminary experiments in Human, Mouse and Rat Liver lysates gave no specific signal but low background (at antibody concentration up to 1µg/ml).IHC: In paraffin embedded Human |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | MLX |
| Gene ID | 6945 |
| Uniprot ID | MLX_HUMAN |
| Accession Number | NP_937848.1; NP_937847.1; NP_733752.1 |
| Immunogen Region | Internal |
| Immunogen Sequence | QIVKAHQDNPHEGED |
| Specificity | This antibody is expected to recognize all three reported isoforms (NP_937848.1; NP_937847.1; NP_733752.1). |
Additional Info
| Function | Transcription regulator. Forms a sequence-specific DNA-binding protein complex with MAD1, MAD4, MNT, WBSCR14 and MLXIP which recognizes the core sequence 5'-CACGTG-3'. The TCFL4-MAD1, TCFL4-MAD4, TCFL4-WBSCR14 complexes are transcriptional repressors. Plays a role in transcriptional activation of glycolytic target genes. Involved in glucose-responsive gene regulation. |
| Protein Name | Max-Like Protein XClass D Basic Helix-Loop-Helix Protein 13Bhlhd13Max-Like Bhlhzip ProteinProtein BigmaxTranscription Factor-Like Protein 4 |
| Database Links | Reactome: R-HSA-163765 |
| Cellular Localisation | Isoform Alpha: CytoplasmFound Predominantly In The CytoplasmIsoform Beta: CytoplasmIsoform Gamma: NucleusFound Predominantly In The Nucleus |
| Alternative Antibody Names | Anti-Max-Like Protein X antibodyAnti-Class D Basic Helix-Loop-Helix Protein 13 antibodyAnti-Bhlhd13 antibodyAnti-Max-Like Bhlhzip Protein antibodyAnti-Protein Bigmax antibodyAnti-Transcription Factor-Like Protein 4 antibodyAnti-MLX antibodyAnti-BHLHD13 antibodyAnti-TCFL4 antibody |
Information sourced from Uniprot.org