• Human malignant melanoma tissue was stained with Anti-Melan-A (ABT-Mart1) Antibody
  • Human malignant melanoma tissue was stained with Anti-Melan-A (ABT-Mart1) Antibody
  • Human malignant melanoma tissue was stained with Anti-Melan-A (ABT-Mart1) Antibody
  • Human malignant melanoma tissue was stained with Anti-Melan-A (ABT-Mart1) Antibody
  • Various whole cell lysates were separated by 10% SDS-PAGE, and the membrane was blotted with anti-Melan-A (ABT-Mart1) antibody. The HRP-conjugated Goat anti- mouse IgG (H + L) antibody was used to detect the antibody. Lane 1: SK-MEL-28 Lane 2: CHL-1 Lane 3: SK-MES-1 Lane 4: A375Predicted band size: 13kDaObserved band size: 18kDa

Anti-MLANA antibody (50-118 aa) [ABT-Mart1] (STJ197030)

SKU:
STJ197030

£168.00 - £226.00
Current Stock:
Host: Mouse
Applications: IHC/IF
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-Melanoma antigen recognized by T-cells 1 (50-118 aa) is suitable for use in Immunohistochemistry and Immunofluorescence research applications.
Clonality: Monoclonal
Clone ID: ABT-Mart1
Conjugation: Unconjugated
Isotype: IgG2bk
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Dilution Range: IHC-P 1:300-500
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: MLANA
Gene ID: 2315
Uniprot ID: MAR1_HUMAN
Immunogen Region: 50-118 aa
Specificity: This antibody detects endogenous levels of human Mart-1/Melan-A. Heat-induced epitope retrieval (HIER) TRIS-EDTA of pH9.0 was highly recommended as antigen repair method in paraffin section. The antib
Immunogen: Synthesized peptide derived from the human Mart-1/Melan-A at the amino acid range 50-118
Post Translational Modifications Acylated.
Function Involved in melanosome biogenesis by ensuring the stability of GPR143. Plays a vital role in the expression, stability, trafficking, and processing of melanocyte protein PMEL, which is critical to the formation of stage II melanosomes.
Protein Name Melanoma Antigen Recognized By T-Cells 1
Mart-1
Antigen Lb39-Aa
Antigen Sk29-Aa
Protein Melan-A
Cellular Localisation Endoplasmic Reticulum Membrane
Single-Pass Type Iii Membrane Protein
Golgi Apparatus
Trans-Golgi Network Membrane
Melanosome
Also Found In Small Vesicles And Tubules Dispersed Over The Entire Cytoplasm
A Small Fraction Of The Protein Is Inserted Into The Membrane In An Inverted Orientation
Inversion Of Membrane Topology Results In The Relocalization Of The Protein From A Predominant Golgi/Post-Golgi Area To The Endoplasmic Reticulum
Melanoma Cells Expressing The Protein With An Inverted Membrane Topology Are More Effectively Recognized By Specific Cytolytic T-Lymphocytes Than Those Expressing The Protein In Its Native Membrane Orientation
Alternative Antibody Names Anti-Melanoma Antigen Recognized By T-Cells 1 antibody
Anti-Mart-1 antibody
Anti-Antigen Lb39-Aa antibody
Anti-Antigen Sk29-Aa antibody
Anti-Protein Melan-A antibody
Anti-MLANA antibody
Anti-MART1 antibody

Information sourced from Uniprot.org

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