• Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using MART-1 Antibody. The picture on the right is blocked with the synthesized peptide.
  • Western blot analysis of lysates from NIH/3T3 cells, using MART-1 Antibody. The lane on the right is blocked with the synthesized peptide.
  • Western blot analysis of 3T3 cells using Melan-A Polyclonal Antibody

Anti-MLANA antibody (41-90 aa) (STJ94093)

SKU:
STJ94093

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Melanoma antigen recognized by T-cells 1 (41-90 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:40000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: MLANA
Gene ID: 2315
Uniprot ID: MAR1_HUMAN
Immunogen Region: 41-90 aa
Specificity: Melan-A Polyclonal Antibody detects endogenous levels of Melan-A protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human MART-1 at the amino acid range 41-90
Post Translational Modifications Acylated.
Function Involved in melanosome biogenesis by ensuring the stability of GPR143. Plays a vital role in the expression, stability, trafficking, and processing of melanocyte protein PMEL, which is critical to the formation of stage II melanosomes.
Protein Name Melanoma Antigen Recognized By T-Cells 1
Mart-1
Antigen Lb39-Aa
Antigen Sk29-Aa
Protein Melan-A
Cellular Localisation Endoplasmic Reticulum Membrane
Single-Pass Type Iii Membrane Protein
Golgi Apparatus
Trans-Golgi Network Membrane
Melanosome
Also Found In Small Vesicles And Tubules Dispersed Over The Entire Cytoplasm
A Small Fraction Of The Protein Is Inserted Into The Membrane In An Inverted Orientation
Inversion Of Membrane Topology Results In The Relocalization Of The Protein From A Predominant Golgi/Post-Golgi Area To The Endoplasmic Reticulum
Melanoma Cells Expressing The Protein With An Inverted Membrane Topology Are More Effectively Recognized By Specific Cytolytic T-Lymphocytes Than Those Expressing The Protein In Its Native Membrane Orientation
Alternative Antibody Names Anti-Melanoma Antigen Recognized By T-Cells 1 antibody
Anti-Mart-1 antibody
Anti-Antigen Lb39-Aa antibody
Anti-Antigen Sk29-Aa antibody
Anti-Protein Melan-A antibody
Anti-MLANA antibody
Anti-MART1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance