Anti-MKLP1 antibody [R07-2H3] (STJA0034569)

SKU:
STJA0034569
£133.50 - £281.50
Processing The item has been added

Host: Rabbit
Applications: WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit monoclonal anti-MKLP1 for use in WB in Human samples. Datasheet included with dilution recommendations, and related reagents.
Clonality : Monoclonal
Clone ID : R07-2H3
Conjugation: Unconjugated
Isotype: IgG
Formulation: 50mM Tris-Glycine (pH 7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Purification: Affinity Purified
Concentration: 0.3 mg/mL
Dilution Range: WB 1:500-1:1000
Storage Instruction: Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles.
Gene Symbol: KIF23
Gene ID: 9493
Uniprot ID: KIF23_HUMAN
Immunogen: A synthetic peptide of human MKLP1
Tissue Specificity Widely expressed.
Post Translational Modifications Ubiquitinated. Deubiquitinated by USP8/UBPY.
Function Component of the centralspindlin complex that serves as a microtubule-dependent and Rho-mediated signaling required for the myosin contractile ring formation during the cell cycle cytokinesis. Essential for cytokinesis in Rho-mediated signaling. Required for the localization of ECT2 to the central spindle. Plus-end-directed motor enzyme that moves antiparallel microtubules in vitro.
Protein Name Kinesin-Like Protein Kif23
Kinesin-Like Protein 5
Mitotic Kinesin-Like Protein 1
Database Links Reactome: R-HSA-2132295
Reactome: R-HSA-6811434
Reactome: R-HSA-68884
Reactome: R-HSA-983189
Cellular Localisation Nucleus
Cytoplasm
Cytoskeleton
Spindle
Midbody
Midbody Ring
Localizes To The Interzone Of Mitotic Spindles
Detected At The Midbody During Later Stages Of Mitotic Cytokinesis
Alternative Antibody Names Anti-Kinesin-Like Protein Kif23 antibody
Anti-Kinesin-Like Protein 5 antibody
Anti-Mitotic Kinesin-Like Protein 1 antibody
Anti-KIF23 antibody
Anti-KNSL5 antibody
Anti-MKLP1 antibody

Information sourced from Uniprot.org