| Short Description : | Mouse monoclonal anti-Mitofilin for use in ELISA, WB, ICC and IP in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | ELISA/WB/ICC/IP |
| Host: | Mouse |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | M027 |
| Isotype: | IgG1 |
| Conjugation: | Unconjugated |
| Purification: | Protein G Purified |
| Dilution Range: | WB 1:1000ICC 1:100IP 1:100 |
| Formulation: | PBS + 1 mg/ml BSA, 0.05% NaN3 and 50% glycerol |
| Storage Instruction: | Storage at-20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at-20°C. |
| Gene Symbol: | IMMT |
| Gene ID: | 10989 |
| Uniprot ID: | MIC60_HUMAN |
| Immunogen: | Clone M027 was generated from a proprietary antigen related to human mitofilin expressed in the A431 epidermoid carcinoma cell line. |
| Immunogen Sequence: | Human |
| Specificity: | Clone M027 detects a 90 kDa* band corresponding to the molecular mass of mitofilin on SDS-PAGE immunoblots of native or denatured human PC3, MDA-MB-231, A431, A549, and MeWo cell lysates, as well as human breast, skin, and brain tissues. In addition, |
| Function | Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Plays an important role in the maintenance of the MICOS complex stability and the mitochondrial cristae morphology. |
| Protein Name | Micos Complex Subunit Mic60Cell Proliferation-Inducing Gene 4/52 ProteinMitochondrial Inner Membrane ProteinMitofilinP87/89 |
| Database Links | Reactome: R-HSA-8949613 |
| Cellular Localisation | Mitochondrion Inner MembraneSingle-Pass Membrane ProteinMitochondrion |
| Alternative Antibody Names | Anti-Micos Complex Subunit Mic60 antibodyAnti-Cell Proliferation-Inducing Gene 4/52 Protein antibodyAnti-Mitochondrial Inner Membrane Protein antibodyAnti-Mitofilin antibodyAnti-P87/89 antibodyAnti-IMMT antibodyAnti-HMP antibodyAnti-MIC60 antibodyAnti-MINOS2 antibodyAnti-PIG4 antibodyAnti-PIG52 antibody |
Information sourced from Uniprot.org
