| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:200-1:2000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MIS12 |
| Gene ID: | 79003 |
| Uniprot ID: | MIS12_HUMAN |
| Immunogen Region: | 1-205 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-205 of human MIS12 (NP_076944.1). |
| Immunogen Sequence: | MSVDPMTYEAQFFGFTPQTC MLRIYIAFQDYLFEVMQAVE QVILKKLDGIPDCDISPVQI RKCTEKFLCFMKGHFDNLFS KMEQLFLQLILRIPSNILLP EDKCKETPYSEEDFQHLQKE IEQLQEKYKTELCTKQALLA ELEEQKIVQAKLKQTLTFFD ELHNVGRDHGTSDFRESLVS LVQNSRKLQNIRDNVEKESK RLKIS |
| Function | Part of the MIS12 complex which is required for normal chromosome alignment and segregation and for kinetochore formation during mitosis. Essential for proper kinetochore microtubule attachments. |
| Protein Name | Protein Mis12 Homolog |
| Database Links | Reactome: R-HSA-141444 Reactome: R-HSA-2467813 Reactome: R-HSA-2500257 Reactome: R-HSA-5663220 Reactome: R-HSA-68877 Reactome: R-HSA-9648025 |
| Cellular Localisation | Chromosome Centromere Kinetochore Associated With The Kinetochore |
| Alternative Antibody Names | Anti-Protein Mis12 Homolog antibody Anti-MIS12 antibody |
Information sourced from Uniprot.org