Host: |
Rabbit |
Applications: |
IHC/WB |
Reactivity: |
Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Mint1 is suitable for use in Immunohistochemistry and Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Lyophilised |
Purification: |
IgG purified |
Dilution Range: |
IHC, WB. A dilution of 1:1000 to 1:2000 is recommended. The optimal dilution should be determined by the end user. |
Storage Instruction: |
Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
Gene Symbol: |
Apba1 |
Gene ID: |
319924 |
Uniprot ID: |
APBA1_MOUSE |
Specificity: |
Specific for MINT1. |
Immunogen: |
A synthetic peptide from mouse Mint1 (APBA1) conjugated to blue carrier protein was used as the antigen. |
Function | Putative function in synaptic vesicle exocytosis by binding to Munc18-1, an essential component of the synaptic vesicle exocytotic machinery. May modulate processing of the amyloid-beta precursor protein (APP) and hence formation of AAP-beta. Component of the LIN-10-LIN-2-LIN-7 complex, which associates with the motor protein KIF17 to transport vesicles containing N-methyl-D-aspartate (NMDA) receptor subunit NR2B along microtubules. |
Protein Name | Amyloid-Beta A4 Precursor Protein-Binding Family A Member 1Adapter Protein X11alphaNeuron-Specific X11 ProteinNeuronal Munc18-1-Interacting Protein 1Mint-1 |
Database Links | Reactome: R-MMU-212676 |
Cellular Localisation | CytoplasmPerinuclear RegionNucleusIsoform 3: Golgi Apparatus |
Alternative Antibody Names | Anti-Amyloid-Beta A4 Precursor Protein-Binding Family A Member 1 antibodyAnti-Adapter Protein X11alpha antibodyAnti-Neuron-Specific X11 Protein antibodyAnti-Neuronal Munc18-1-Interacting Protein 1 antibodyAnti-Mint-1 antibodyAnti-Apba1 antibodyAnti-Mint1 antibodyAnti-mLin-10 antibodyAnti-X11 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance