Anti-MIEN1 antibody (80-130) {Biotin} (STJ503560)

SKU:
STJ503560-100

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Host: Rabbit
Applications: ELISA/WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-MIEN1 (80-130) is suitable for use in ELISA and Western Blot research applications.
Clonality: Polyclonal
Conjugation: Biotin
Isotype: IgG
Purification: Affinity Purified
Concentration: 0.65-0.83 µg/µl
Dilution Range: WB: 1:500-1:1, 000
DB: 1:2, 000
ELISA: 1:2, 000
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: MIEN1
Gene ID: 84299
Uniprot ID: MIEN1_HUMAN
Immunogen Region: 80-130
Immunogen: Synthetic peptide taken within amino acid region 80-130 on human XTP4 protein.
Tissue Specificity Among normal tissues, present only in Leydig cells. Strongly up-regulated in breast cancers and in brain cancer distant metastasis (at protein level). Up-regulated in prostate cancer cells and in the higher grades of prostate adenocarcinoma (at protein level).
Post Translational Modifications Isoprenylation facilitates association with the plasma membrane and enhances the migratory phenotype of cells by inducing increased filopodia formation.
Function Increases cell migration by inducing filopodia formation at the leading edge of migrating cells. Plays a role in regulation of apoptosis, possibly through control of CASP3. May be involved in a redox-related process.
Protein Name Migration And Invasion Enhancer 1
Hbv X-Transactivated Gene 4 Protein
Hbv Xag-Transactivated Protein 4
Protein C35
Cellular Localisation Cytoplasm
Cytosol
Cell Membrane
Lipid-Anchor
Cytoplasmic Side
Concentrates At The Leading Edge Of Migrating Cells
Localizes Outside Membrane Raft Regions
Alternative Antibody Names Anti-Migration And Invasion Enhancer 1 antibody
Anti-Hbv X-Transactivated Gene 4 Protein antibody
Anti-Hbv Xag-Transactivated Protein 4 antibody
Anti-Protein C35 antibody
Anti-MIEN1 antibody
Anti-C17orf37 antibody
Anti-RDX12 antibody
Anti-XTP4 antibody

Information sourced from Uniprot.org

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