| Host: | Rabbit |
| Applications: | ELISA/WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-MIEN1 (20-70) is suitable for use in ELISA and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Biotin |
| Isotype: | IgG |
| Formulation: | Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide). |
| Purification: | Affinity Purified |
| Concentration: | 0.65-0.83 µg/µl |
| Dilution Range: | WB: 1:500-1:1, 000 DB: 1:2, 000 ELISA: 1:2, 000 |
| Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: | MIEN1 |
| Gene ID: | 84299 |
| Uniprot ID: | MIEN1_HUMAN |
| Immunogen Region: | 20-70 |
| Immunogen: | Synthetic peptide taken within amino acid region 20-70 on human XTP4 protein. |
| Tissue Specificity | Among normal tissues, present only in Leydig cells. Strongly up-regulated in breast cancers and in brain cancer distant metastasis (at protein level). Up-regulated in prostate cancer cells and in the higher grades of prostate adenocarcinoma (at protein level). |
| Post Translational Modifications | Isoprenylation facilitates association with the plasma membrane and enhances the migratory phenotype of cells by inducing increased filopodia formation. |
| Function | Increases cell migration by inducing filopodia formation at the leading edge of migrating cells. Plays a role in regulation of apoptosis, possibly through control of CASP3. May be involved in a redox-related process. |
| Protein Name | Migration And Invasion Enhancer 1 Hbv X-Transactivated Gene 4 Protein Hbv Xag-Transactivated Protein 4 Protein C35 |
| Cellular Localisation | Cytoplasm Cytosol Cell Membrane Lipid-Anchor Cytoplasmic Side Concentrates At The Leading Edge Of Migrating Cells Localizes Outside Membrane Raft Regions |
| Alternative Antibody Names | Anti-Migration And Invasion Enhancer 1 antibody Anti-Hbv X-Transactivated Gene 4 Protein antibody Anti-Hbv Xag-Transactivated Protein 4 antibody Anti-Protein C35 antibody Anti-MIEN1 antibody Anti-C17orf37 antibody Anti-RDX12 antibody Anti-XTP4 antibody |
Information sourced from Uniprot.org