| Tissue Specificity | Q29983 - Widely expressed with the exception of the central nervous system where it is absent. Expressed predominantly in gastric epithelium and also in monocytes, keratinocytes, endothelial cells, fibroblasts and in the outer layer of Hassal's corpuscles within the medulla of normal thymus. In skin, expressed mainly in the keratin layers, basal cells, ducts and follicles. Also expressed in many, but not all, epithelial tumors of lung, breast, kidney, ovary, prostate and colon. In thyomas, overexpressed in cortical and medullar epithelial cells. Tumors expressing MICA display increased levels of gamma delta T-cells.Q29980 - Widely expressed with the exception of the central nervous system where it is absent. Expressed in many, but not all, epithelial tumors of lung, breast, kidney, ovary, prostate and colon. In hepatocellular carcinomas, expressed in tumor cells but not in surrounding non-cancerous tissue. |
| Alternative Antibody Names | Anti-Mhc Class I Polypeptide-Related Sequence A antibodyAnti-Mic-A antibodyAnti-MICA antibodyAnti-PERB11.1 antibodyAnti-Mhc Class I Polypeptide-Related Sequence B antibodyAnti-Mic-B antibodyAnti-MICB antibodyAnti-PERB11.2 antibody |
Information sourced from Uniprot.org
