Anti-MGST3 antibody (8-57 aa) (STJ94118)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human MGST3 at the amino acid range 8-57
General Information
| Short Description | Rabbit polyclonal anti-Glutathione S-transferase 3, mitochondrial (8-57 aa) for use in IHC, IF and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | IHC 1:100-1:300ELISA 1:10000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MGST3 |
| Gene ID | 4259 |
| Uniprot ID | MGST3_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human MGST3 at the amino acid range 8-57 |
| Immunogen Region | 8-57 aa |
| Specificity | MGST3 Polyclonal Antibody detects endogenous levels of MGST3 protein. |
Additional Info
| Function | Displays both glutathione S-transferase and glutathione peroxidase activities toward oxyeicosanoids, as part of cellular detoxification as well as synthesis of bioactive metabolites. Catalyzes conjugate addition of reduced glutathione to the alpha, beta-unsaturated C=C carbonyl group of eisosanoids such as leukotriene A4 and 15-deoxy-Delta12,14-prostaglandin J2 to form GSH adducts relevant to the inflammatory response. Catalyzes glutathione-dependent reduction of eicosanoid peroxides to yield the corresponding eicosanoid hydroxides. |
| Protein Name | Glutathione S-Transferase 3 - MitochondrialGst-3Glutathione Peroxidase Mgst3Ltc4 Synthase Mgst3 |
| Database Links | Reactome: R-HSA-156590Reactome: R-HSA-5423646 |
| Cellular Localisation | Mitochondrion Outer MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Glutathione S-Transferase 3 - Mitochondrial antibodyAnti-Gst-3 antibodyAnti-Glutathione Peroxidase Mgst3 antibodyAnti-Ltc4 Synthase Mgst3 antibodyAnti-MGST3 antibody |
Information sourced from Uniprot.org