| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-MGAM (860-1090) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
MGAM |
| Gene ID: |
8972 |
| Uniprot ID: |
MGA_HUMAN |
| Immunogen Region: |
860-1090 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 860-1090 of human MGAM (NP_004659.2). |
| Immunogen Sequence: |
ETKDTVANKVYLLCEFSVTQ NRLEVNISQSTYKDPNNLAF NEIKILGTEEPSNVTVKHNG VPSQTSPTVTYDSNLKVAII TDIDLLLGEAYTVEWSIKIR DEEKIDCYPDENGASAENCT ARGCIWEASNSSGVPFCYFV NDLYSVSDVQYNSHGATADI SLKSSVYANAFPSTPVNPLR LDVTYHKNEMLQFKIYDPNK NRYEVPVPLNIPSMPSSTPE GQLYDVLIKKN |
| Tissue Specificity | Broadly expressed. Highly expressed in small intestine. Expressed in granulocytes. |
| Post Translational Modifications | N- and O-glycosylated. Does not undergo intracellular or extracellular proteolytic cleavage. Sulfated. |
| Function | Alpha-(1,4) exo-glucosidase involved in breakdown of dietary starch oligosaccharides in small intestine. Cleaves the non-reducing alpha-(1,4)-linked glucose residue in linear dextrins with retention of anomeric center stereochemistry. Mainly hydrolyzes short length oligomaltoses having two to seven glucose residues. Can cleave alpha-(1,2), alpha-(1,3) and alpha-(1,6) glycosidic linkages with lower efficiency, whereas beta glycosidic linkages are usually not hydrolyzed. |
| Protein Name | Maltase-GlucoamylaseAlpha-1 -4-Glucosidase |
| Database Links | Reactome: R-HSA-189085Reactome: R-HSA-6798695 |
| Cellular Localisation | Apical Cell MembraneSingle-Pass Type Ii Membrane ProteinBrush Border |
| Alternative Antibody Names | Anti-Maltase-Glucoamylase antibodyAnti-Alpha-1 -4-Glucosidase antibodyAnti-MGAM antibodyAnti-MGA antibodyAnti-MGAML antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
