| Host: | Rabbit |
| Applications: | WB/IHC-P/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MFF |
| Gene ID: | 56947 |
| Uniprot ID: | MFF_HUMAN |
| Immunogen Region: | 1-100 |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MFF (NP_064579.3). |
| Immunogen Sequence: | MSKGTSSDTSLGRVSRAAFP SPTAAEMAEISRIQYEMEYT EGISQRMRVPEKLKVAPPNA DLEQGFQEGVPNASVIMQVP ERIVVAGNNEDVSFSRPADL |
| Tissue Specificity | Highly expressed in heart, kidney, liver, brain, muscle, and stomach. |
| Function | Plays a role in mitochondrial and peroxisomal fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface. May be involved in regulation of synaptic vesicle membrane dynamics by recruitment of DNM1L to clathrin-containing vesicles. |
| Protein Name | Mitochondrial Fission Factor |
| Cellular Localisation | Mitochondrion Outer MembraneSingle-Pass Type Iv Membrane ProteinPeroxisomeCytoplasmic VesicleSecretory VesicleSynaptic Vesicle |
| Alternative Antibody Names | Anti-Mitochondrial Fission Factor antibodyAnti-MFF antibodyAnti-C2orf33 antibodyAnti-AD030 antibodyAnti-AD033 antibodyAnti-GL004 antibody |
Information sourced from Uniprot.org