Post Translational Modifications | Forms intermolecular disulfide bonds either with other MAGP-2 molecules or with other components of the microfibrils. N- and O-glycosylated. O-glycosylated with core 1 or possibly core 8 glycans. O-glycan heterogeneity at Thr-54: HexHexNAc (major) and HexHexNAc + sulfate (minor). |
Function | May play a role in hematopoiesis. In the cardiovascular system, could regulate growth factors or participate in cell signaling in maintaining large vessel integrity. Component of the elastin-associated microfibrils. |
Protein Name | Microfibrillar-Associated Protein 5Mfap-5Mp25Microfibril-Associated Glycoprotein 2Magp-2 |
Database Links | Reactome: R-HSA-1566948Reactome: R-HSA-2129379 |
Cellular Localisation | SecretedExtracellular SpaceExtracellular Matrix |
Alternative Antibody Names | Anti-Microfibrillar-Associated Protein 5 antibodyAnti-Mfap-5 antibodyAnti-Mp25 antibodyAnti-Microfibril-Associated Glycoprotein 2 antibodyAnti-Magp-2 antibodyAnti-MFAP5 antibodyAnti-MAGP2 antibody |
Information sourced from Uniprot.org