• STJ72803 (0. 2µg/ml) staining of Mouse Testis (+/+ is wt, trp/trp is knock-down) lysate (35µg protein in RIPA buffer). Data obtained by Dr. B. Lu, Wake Forest Baptist Medical Center, Winston-Salem, NC, USA. Detected by chemiluminescence.

Anti-MEX3C antibody (541-554) (STJ72803)

SKU:
STJ72803-100

£303.50
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Host: Goat
Applications: Pep-ELISA/WB/IHC
Reactivity: Human/Mouse/Rat/Dog/Pig/Cow
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Goat polyclonal antibody anti-MEX3C (541-554) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: WB-0.2-0.5µg/ml
IHC-5µg/ml
ELISA-antibody detection limit dilution 1:32000.
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: MEX3C
Gene ID: 51320
Uniprot ID: MEX3C_HUMAN
Immunogen Region: 541-554
Accession Number: NP_057710.3
Immunogen Sequence: TPRLSPTFPESIEH
Function E3 ubiquitin ligase responsible for the post-transcriptional regulation of common HLA-A allotypes. Binds to the 3' UTR of HLA-A2 mRNA, and regulates its levels by promoting mRNA decay. RNA binding is sufficient to prevent translation, but ubiquitin ligase activity is required for mRNA degradation.
Protein Name Rna-Binding E3 Ubiquitin-Protein Ligase Mex3c
Ring Finger And Kh Domain-Containing Protein 2
Ring Finger Protein 194
Ring-Type E3 Ubiquitin Transferase Mex3c
Database Links Reactome: R-HSA-983168
Cellular Localisation Cytoplasm
Nucleus
Predominantly Expressed In The Cytoplasm And Shuttles Between The Cytoplasm And The Nucleus Through The Crm1 Export Pathway
May Act As Suppressor Of Replication Stress And Chromosome Missegregation
Alternative Antibody Names Anti-Rna-Binding E3 Ubiquitin-Protein Ligase Mex3c antibody
Anti-Ring Finger And Kh Domain-Containing Protein 2 antibody
Anti-Ring Finger Protein 194 antibody
Anti-Ring-Type E3 Ubiquitin Transferase Mex3c antibody
Anti-MEX3C antibody
Anti-RKHD2 antibody
Anti-RNF194 antibody
Anti-BM-013 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance