| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | METTL21C |
| Gene ID: | 196541 |
| Uniprot ID: | MT21C_HUMAN |
| Immunogen Region: | 1-264 |
| Immunogen Sequence: | MDVCLSSAQQPGRRGEGLSS PGGWLEAEKKGAPQKDSTGG VLEESNKIEPSLHSLQKFVP TDYASYTQEHYRFAGKEIVI QESIESYGAVVWPGAMALCQ YLEEHAEELNFQDAKILEIG AGPGLVSIVASILGAQVTAT DLPDVLGNLQYNLLKNTLQC TAHLPEVKELVWGEDLDKNF PKSAFYYDYVLASDVVYHHY FLDKLLTTMVYLSQPGTVLL WANKFRFSTDYEFLDKFKQ |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-264 of human METTL21C (NP_001010977.1). |
| Function | Protein-lysine N-methyltransferase using S-adenosyl-L-methionine as methyl donor. Mono-di and trimethylates 'Lys-943' of AARS1. |
| Protein Name | Protein-Lysine Methyltransferase Mettl21cMethyltransferase-Like Protein 21c |
| Database Links | |
| Cellular Localisation | NucleusCytoplasm |
| Alternative Antibody Names | Anti-Protein-Lysine Methyltransferase Mettl21c antibodyAnti-Methyltransferase-Like Protein 21c antibodyAnti-METTL21C antibodyAnti-C13orf39 antibody |
Information sourced from Uniprot.org
![Western blot analysis of lysates from wild type (WT) and AES knockout (KO) HeLa cells, using [KO Validated] AES Rabbit polyclonal antibody (STJ11100820) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/600x533/products/89756/358232/STJ11100820_1__13212.1713122563.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and AES knockout (KO) HeLa cells, using [KO Validated] AES Rabbit polyclonal antibody (STJ11100820) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.")
