| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: |
U2AF1 |
| Gene ID: |
102724594/7307 |
| Uniprot ID: |
U2AF1_HUMAN |
| Specificity: |
A synthetic methylated peptide around H37 of human U2AF1 (NP_006749.1). |
| Immunogen Sequence: |
RLHNK |
| Function | Plays a critical role in both constitutive and enhancer-dependent splicing by mediating protein-protein interactions and protein-RNA interactions required for accurate 3'-splice site selection. Recruits U2 snRNP to the branch point. Directly mediates interactions between U2AF2 and proteins bound to the enhancers and thus may function as a bridge between U2AF2 and the enhancer complex to recruit it to the adjacent intron. |
| Protein Name | Splicing Factor U2af 35 Kda SubunitU2 Auxiliary Factor 35 Kda SubunitU2 Small Nuclear Rna Auxiliary Factor 1U2 Snrnp Auxiliary Factor Small Subunit |
| Database Links | Reactome: R-HSA-159236Reactome: R-HSA-72163Reactome: R-HSA-72187Reactome: R-HSA-73856 |
| Cellular Localisation | NucleusNucleus Speckle |
| Alternative Antibody Names | Anti-Splicing Factor U2af 35 Kda Subunit antibodyAnti-U2 Auxiliary Factor 35 Kda Subunit antibodyAnti-U2 Small Nuclear Rna Auxiliary Factor 1 antibodyAnti-U2 Snrnp Auxiliary Factor Small Subunit antibodyAnti-U2AF1 antibodyAnti-U2AF35 antibodyAnti-U2AFBP antibodyAnti-FP793 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
