Function | Plays a critical role in both constitutive and enhancer-dependent splicing by mediating protein-protein interactions and protein-RNA interactions required for accurate 3'-splice site selection. Recruits U2 snRNP to the branch point. Directly mediates interactions between U2AF2 and proteins bound to the enhancers and thus may function as a bridge between U2AF2 and the enhancer complex to recruit it to the adjacent intron. |
Protein Name | Splicing Factor U2af 35 Kda SubunitU2 Auxiliary Factor 35 Kda SubunitU2 Small Nuclear Rna Auxiliary Factor 1U2 Snrnp Auxiliary Factor Small Subunit |
Database Links | Reactome: R-HSA-159236Reactome: R-HSA-72163Reactome: R-HSA-72187Reactome: R-HSA-73856 |
Cellular Localisation | NucleusNucleus Speckle |
Alternative Antibody Names | Anti-Splicing Factor U2af 35 Kda Subunit antibodyAnti-U2 Auxiliary Factor 35 Kda Subunit antibodyAnti-U2 Small Nuclear Rna Auxiliary Factor 1 antibodyAnti-U2 Snrnp Auxiliary Factor Small Subunit antibodyAnti-U2AF1 antibodyAnti-U2AF35 antibodyAnti-U2AFBP antibodyAnti-FP793 antibody |
Information sourced from Uniprot.org