| Tissue Specificity | Overexpressed in colon cancer cell lines and colon tumors as compared to normal tissues (at protein level). |
| Function | Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. May play a role in colon tumorigenesis. |
| Protein Name | Methionine Aminopeptidase 1d - MitochondrialMap 1dMetap 1dMethionyl Aminopeptidase Type 1d - MitochondrialPeptidase M 1d |
| Cellular Localisation | Mitochondrion |
| Alternative Antibody Names | Anti-Methionine Aminopeptidase 1d - Mitochondrial antibodyAnti-Map 1d antibodyAnti-Metap 1d antibodyAnti-Methionyl Aminopeptidase Type 1d - Mitochondrial antibodyAnti-Peptidase M 1d antibodyAnti-METAP1D antibodyAnti-MAP1D antibody |
Information sourced from Uniprot.org
