• Anti-Melanoma Associated Antigen antibody [NKI/beteb] (STJ16100735)

Anti-Melanoma Associated Antigen antibody [NKI/beteb] (STJ16100735)

SKU:
STJ16100735-1

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Host: Mouse
Applications: IHC-P/IHC-F/IF
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-Melanoma Associated antigen is suitable for use in Immunohistochemistry and Immunofluorescence research applications.
Clonality: Monoclonal
Clone ID: NKI/beteb
Conjugation: Unconjugated
Isotype: IgG2b
Formulation: PBS with 0.1% BSA and 0.02% sodium azide
Concentration: 100 ug/mL
Storage Instruction: Store at 2-8°C upon receipt.
Background Melanoma associated antigen (MAA) is dispersed in the cytoplasma of melanoma cells, and is more concentrated inside vacuoles and sometimes on the melanosomes. Occasionally the antigen is seen on the cell surface. The antigen is actively shed from living cells. Although the antigen is associated with melanomas, it is not codistributed with the tyrosinase activity associated with melagonesis. The antigen shows codistribution with cathepsin D, which is a marker for lysosomal functions. The antibody NKI/beteb recognizes a (pre) melanosomal 100 kD and 7 kD antigen (glycoprotein). The antibody reacts with melanomas, clear cells sarcomas (melanoma of soft tissue) , nevocellular nevi, and normal melanocytes. Except for one case of non-Hodgkin s lymphoma in which macrophages were positive, no reactions with other tumors or tissues have been observed.

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance