Host: | Mouse |
Applications: | IHC-P |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Mouse monoclonal antibody anti-Melan A is suitable for use in Immunohistochemistry research applications. |
Clonality : | Monoclonal |
Clone ID : | A103 |
Conjugation: | Unconjugated |
Isotype: | IgG1 |
Formulation: | Tissue culture supernatant with sodium azide |
Concentration: | >=22 mg/L |
Dilution Range: | IHC-P 1:50 |
Storage Instruction: | Store at 2-8°C upon receipt. |
Immunogen: | Prokaryotic recombinant fusion protein corresponding to the human melan A molecule. |
Background | Melan A, a product of the MART-1 gene, is a melanocyte differentiation marker recognized by autologous cytotoxic T lymphocytes. Other melanoma-associated markers recognized by autologous cytotoxic T cells are reported to include MAGE-1, MAGE-3, tyrosinase, gp100, gp75, BAGE-1 and GAGE-1. The analysis of these different molecules and their expression in individual melanomas may be of help in the study of their particular molecular roles in melanocyte differentiation and tumorigenesis. |
Information sourced from Uniprot.org