| Function | Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. May be part of a complex containing NF2/merlin that participates in cellular signaling to the actin cytoskeleton downstream of tyrosine kinase signaling pathways. |
| Protein Name | Mediator Of Rna Polymerase Ii Transcription Subunit 28Endothelial-Derived Protein 1Mediator Complex Subunit 28Merlin And Grb2-Interacting Cytoskeletal ProteinMagicinTumor Angiogenesis Marker Eg-1 |
| Database Links | Reactome: R-HSA-1989781Reactome: R-HSA-381340Reactome: R-HSA-9833110 |
| Cellular Localisation | NucleusCytoplasmMembranePeripheral Membrane ProteinIt Is Cytoplasmic And Mainly Membrane-Associated |
| Alternative Antibody Names | Anti-Mediator Of Rna Polymerase Ii Transcription Subunit 28 antibodyAnti-Endothelial-Derived Protein 1 antibodyAnti-Mediator Complex Subunit 28 antibodyAnti-Merlin And Grb2-Interacting Cytoskeletal Protein antibodyAnti-Magicin antibodyAnti-Tumor Angiogenesis Marker Eg-1 antibodyAnti-MED28 antibodyAnti-EG1 antibodyAnti-FKSG20 antibody |
Information sourced from Uniprot.org
