Anti-MED24 antibody (1-160) (STJ110362)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal MED24 (1-160) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MED24 |
| Gene ID | 9862 |
| Uniprot ID | MED24_HUMAN |
| Immunogen Region | 1-160 |
| Immunogen Sequence | MKVVNLKQAILQAWKERWSD YQWAINMKKFFPKGATWDIL NLADALLEQAMIGPSPNPLI LSYLKYAISSQMVSYSSVLT AISKFDDFSRDLCVQALLDI MDMFCDRLSCHGKAEECIGL CRALLSALHWLLRCTAASAE RLREGLEAGTPAAGEKQLAM |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-160 of human MED24 (NP_055630.2). |
Additional Info
| Tissue Specificity | Ubiquitous. Abundant in skeletal muscle, heart and placenta. |
| Function | Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. |
| Protein Name | Mediator Of Rna Polymerase Ii Transcription Subunit 24Activator-Recruited Cofactor 100 Kda ComponentArc100Cofactor Required For Sp1 Transcriptional Activation Subunit 4Crsp Complex Subunit 4Mediator Complex Subunit 24Thyroid Hormone Receptor-Associated Protein 4Thyroid Hormone Receptor-Associated Protein Complex 100 Kda ComponentTrap100Htrap100Vitamin D3 Receptor-Interacting Protein Complex 100 Kda ComponentDrip100 |
| Database Links | Reactome: R-HSA-1989781Reactome: R-HSA-212436Reactome: R-HSA-381340Reactome: R-HSA-9833110Reactome: R-HSA-9841922 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Mediator Of Rna Polymerase Ii Transcription Subunit 24 antibodyAnti-Activator-Recruited Cofactor 100 Kda Component antibodyAnti-Arc100 antibodyAnti-Cofactor Required For Sp1 Transcriptional Activation Subunit 4 antibodyAnti-Crsp Complex Subunit 4 antibodyAnti-Mediator Complex Subunit 24 antibodyAnti-Thyroid Hormone Receptor-Associated Protein 4 antibodyAnti-Thyroid Hormone Receptor-Associated Protein Complex 100 Kda Component antibodyAnti-Trap100 antibodyAnti-Htrap100 antibodyAnti-Vitamin D3 Receptor-Interacting Protein Complex 100 Kda Component antibodyAnti-Drip100 antibodyAnti-MED24 antibodyAnti-ARC100 antibodyAnti-CRSP4 antibodyAnti-DRIP100 antibodyAnti-KIAA0130 antibodyAnti-THRAP4 antibodyAnti-TRAP100 antibody |
Information sourced from Uniprot.org