| Tissue Specificity | Ubiquitous. Abundant in skeletal muscle, heart and placenta. |
| Function | Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. |
| Protein Name | Mediator Of Rna Polymerase Ii Transcription Subunit 24Activator-Recruited Cofactor 100 Kda ComponentArc100Cofactor Required For Sp1 Transcriptional Activation Subunit 4Crsp Complex Subunit 4Mediator Complex Subunit 24Thyroid Hormone Receptor-Associated Protein 4Thyroid Hormone Receptor-Associated Protein Complex 100 Kda ComponentTrap100Htrap100Vitamin D3 Receptor-Interacting Protein Complex 100 Kda ComponentDrip100 |
| Database Links | Reactome: R-HSA-1989781Reactome: R-HSA-212436Reactome: R-HSA-381340Reactome: R-HSA-9833110 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Mediator Of Rna Polymerase Ii Transcription Subunit 24 antibodyAnti-Activator-Recruited Cofactor 100 Kda Component antibodyAnti-Arc100 antibodyAnti-Cofactor Required For Sp1 Transcriptional Activation Subunit 4 antibodyAnti-Crsp Complex Subunit 4 antibodyAnti-Mediator Complex Subunit 24 antibodyAnti-Thyroid Hormone Receptor-Associated Protein 4 antibodyAnti-Thyroid Hormone Receptor-Associated Protein Complex 100 Kda Component antibodyAnti-Trap100 antibodyAnti-Htrap100 antibodyAnti-Vitamin D3 Receptor-Interacting Protein Complex 100 Kda Component antibodyAnti-Drip100 antibodyAnti-MED24 antibodyAnti-ARC100 antibodyAnti-CRSP4 antibodyAnti-DRIP100 antibodyAnti-KIAA0130 antibodyAnti-THRAP4 antibodyAnti-TRAP100 antibody |
Information sourced from Uniprot.org
