| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-MED23 (890-1110) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
MED23 |
| Gene ID: |
9439 |
| Uniprot ID: |
MED23_HUMAN |
| Immunogen Region: |
890-1110 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 890-1110 of human MED23 (NP_001257450.1). |
| Immunogen Sequence: |
LLKPNDFRNRVSDFVKENSP EHWLQNDWHTKHMNYHKKYP EKLYFEGLAEQVDPPVQIQS PYLPIYFGNVCLRFLPVFDI VIHRFLELLPVSKSLETLLD HLGGLYKFHDRPVTYLYNTL HYYEMHLRDRAFLKRKLVHA IIGSLKDNRPQGWCLSDTYL KCAMNAREENPWVPDDTYYC RLIGRLVDTMAGKSPGPFPN CDWRFNEFPNPAAHALHVTC V |
| Function | Required for transcriptional activation subsequent to the assembly of the pre-initiation complex. Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional pre-initiation complex with RNA polymerase II and the general transcription factors. Required for transcriptional activation by adenovirus E1A protein. Required for ELK1-dependent transcriptional activation in response to activated Ras signaling. |
| Protein Name | Mediator Of Rna Polymerase Ii Transcription Subunit 23Activator-Recruited Cofactor 130 Kda ComponentArc130Cofactor Required For Sp1 Transcriptional Activation Subunit 3Crsp Complex Subunit 3Mediator Complex Subunit 23Protein Sur-2 HomologHsur-2Transcriptional Coactivator Crsp130Vitamin D3 Receptor-Interacting Protein Complex 130 Kda ComponentDrip130 |
| Database Links | Reactome: R-HSA-1989781Reactome: R-HSA-212436Reactome: R-HSA-381340 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Mediator Of Rna Polymerase Ii Transcription Subunit 23 antibodyAnti-Activator-Recruited Cofactor 130 Kda Component antibodyAnti-Arc130 antibodyAnti-Cofactor Required For Sp1 Transcriptional Activation Subunit 3 antibodyAnti-Crsp Complex Subunit 3 antibodyAnti-Mediator Complex Subunit 23 antibodyAnti-Protein Sur-2 Homolog antibodyAnti-Hsur-2 antibodyAnti-Transcriptional Coactivator Crsp130 antibodyAnti-Vitamin D3 Receptor-Interacting Protein Complex 130 Kda Component antibodyAnti-Drip130 antibodyAnti-MED23 antibodyAnti-ARC130 antibodyAnti-CRSP3 antibodyAnti-DRIP130 antibodyAnti-KIAA1216 antibodyAnti-SUR2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
