Anti-MED18 antibody (1-208) (STJ116798)

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STJ116798
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:1000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: MED18
Gene ID: 54797
Uniprot ID: MED18_HUMAN
Immunogen Region: 1-208
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 1-208 of human MED18 (NP_001120822.1).
Immunogen Sequence: MEAPPVTMMPVTGGTINMME YLLQGSVLDHSLESLIHRLR GLCDNMEPETFLDHEMVFLL KGQQASPFVLRARRSMDRAG APWHLRYLGQPEMGDKNRHA LVRNCVDIATSENLTDFLME MGFRMDHEFVAKGHLFRKGI MKIMVYKIFRILVPGNTDST EALSLSYLVELSVVAPAGQD MVSDDMKNFAEQLKPLVHLE KIDPKRLM
Function Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Protein Name Mediator Of Rna Polymerase Ii Transcription Subunit 18
Mediator Complex Subunit 18
P28b
Database Links Reactome: R-HSA-1989781
Reactome: R-HSA-381340
Reactome: R-HSA-9833110
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Mediator Of Rna Polymerase Ii Transcription Subunit 18 antibody
Anti-Mediator Complex Subunit 18 antibody
Anti-P28b antibody
Anti-MED18 antibody

Information sourced from Uniprot.org