| Tissue Specificity | Ubiquitous. |
| Function | Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. |
| Protein Name | Mediator Of Rna Polymerase Ii Transcription Subunit 17Activator-Recruited Cofactor 77 Kda ComponentArc77Cofactor Required For Sp1 Transcriptional Activation Subunit 6Crsp Complex Subunit 6Mediator Complex Subunit 17Thyroid Hormone Receptor-Associated Protein Complex 80 Kda ComponentTrap80Transcriptional Coactivator Crsp77Vitamin D3 Receptor-Interacting Protein Complex 80 Kda ComponentDrip80 |
| Database Links | Reactome: R-HSA-1989781Reactome: R-HSA-212436Reactome: R-HSA-381340Reactome: R-HSA-9833110 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Mediator Of Rna Polymerase Ii Transcription Subunit 17 antibodyAnti-Activator-Recruited Cofactor 77 Kda Component antibodyAnti-Arc77 antibodyAnti-Cofactor Required For Sp1 Transcriptional Activation Subunit 6 antibodyAnti-Crsp Complex Subunit 6 antibodyAnti-Mediator Complex Subunit 17 antibodyAnti-Thyroid Hormone Receptor-Associated Protein Complex 80 Kda Component antibodyAnti-Trap80 antibodyAnti-Transcriptional Coactivator Crsp77 antibodyAnti-Vitamin D3 Receptor-Interacting Protein Complex 80 Kda Component antibodyAnti-Drip80 antibodyAnti-MED17 antibodyAnti-ARC77 antibodyAnti-CRSP6 antibodyAnti-DRIP77 antibodyAnti-DRIP80 antibodyAnti-TRAP80 antibody |
Information sourced from Uniprot.org
