| Host: |
Rabbit |
| Applications: |
WB/IHC/IF/ELISA |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Mediator of RNA polymerase II transcription subunit 13-like (449-498 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-1:2000IHC 1:100-1:300ELISA 1:10000IF 1:50-200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
MED13L |
| Gene ID: |
23389 |
| Uniprot ID: |
MD13L_HUMAN |
| Immunogen Region: |
449-498 aa |
| Specificity: |
TRAP240 Polyclonal Antibody detects endogenous levels of TRAP240 protein. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from the human MED13L at the amino acid range 449-498 |
| Function | Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. This subunit may specifically regulate transcription of targets of the Wnt signaling pathway and SHH signaling pathway. |
| Protein Name | Mediator Of Rna Polymerase Ii Transcription Subunit 13-LikeMediator Complex Subunit 13-LikeThyroid Hormone Receptor-Associated Protein 2Thyroid Hormone Receptor-Associated Protein Complex 240 Kda Component-Like |
| Database Links | Reactome: R-HSA-1989781Reactome: R-HSA-381340 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Mediator Of Rna Polymerase Ii Transcription Subunit 13-Like antibodyAnti-Mediator Complex Subunit 13-Like antibodyAnti-Thyroid Hormone Receptor-Associated Protein 2 antibodyAnti-Thyroid Hormone Receptor-Associated Protein Complex 240 Kda Component-Like antibodyAnti-MED13L antibodyAnti-KIAA1025 antibodyAnti-PROSIT240 antibodyAnti-THRAP2 antibodyAnti-TRAP240L antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
