| Host: | Rabbit |
| Applications: | WB/IHC-P/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ME3 |
| Gene ID: | 10873 |
| Uniprot ID: | MAON_HUMAN |
| Immunogen Region: | 505-604 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 505-604 of human ME3 (NP_001014811.1). |
| Immunogen Sequence: | IRHIPDEIFLLTAEQIAQEV SEQHLSQGRLYPPLSTIRDV SLRIAIKVLDYAYKHNLASY YPEPKDKEAFVRSLVYTPDY DSFTLDSYTWPKEAMNVQTV |
| Tissue Specificity | Expressed predominantly in organs with a low-division rate. |
| Function | Catalyzes the oxidative decarboxylation of (S)-malate to pyruvate using NADP(+) as a cofactor. Can also reverse the decarboxylation reaction, but only with significantly lower efficiency. |
| Protein Name | Nadp-Dependent Malic Enzyme - MitochondrialNadp-MeMalic Enzyme 3 |
| Database Links | Reactome: R-HSA-70268 |
| Cellular Localisation | Mitochondrion Matrix |
| Alternative Antibody Names | Anti-Nadp-Dependent Malic Enzyme - Mitochondrial antibodyAnti-Nadp-Me antibodyAnti-Malic Enzyme 3 antibodyAnti-ME3 antibody |
Information sourced from Uniprot.org