Anti-MDH1 antibody (STJ193110)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from part of the human protein
General Information
| Short Description | Rabbit polyclonal anti-Malate dehydrogenase, cytoplasmic for use in WB and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MDH1 |
| Gene ID | 4190 |
| Uniprot ID | MDHC_HUMAN |
| Immunogen | Synthesized peptide derived from part of the human protein |
| Specificity | MDHC Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Function | Catalyzes the reduction of aromatic alpha-keto acids in the presence of NADH. Plays essential roles in the malate-aspartate shuttle and the tricarboxylic acid cycle, important in mitochondrial NADH supply for oxidative phosphorylation. Catalyzes the reduction of 2-oxoglutarate to 2-hydroxyglutarate, leading to elevated reactive oxygen species (ROS). |
| Protein Name | Malate Dehydrogenase - CytoplasmicAromatic Alpha-Keto Acid ReductaseKarCytosolic Malate Dehydrogenase |
| Database Links | Reactome: R-HSA-9856872 |
| Cellular Localisation | CytoplasmCytosol |
| Alternative Antibody Names | Anti-Malate Dehydrogenase - Cytoplasmic antibodyAnti-Aromatic Alpha-Keto Acid Reductase antibodyAnti-Kar antibodyAnti-Cytosolic Malate Dehydrogenase antibodyAnti-MDH1 antibodyAnti-MDHA antibody |
Information sourced from Uniprot.org