| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Microspherule protein 1 is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
MCRS1 |
| Gene ID: |
10445 |
| Uniprot ID: |
MCRS1_HUMAN |
| Specificity: |
This antibody detects endogenous levels of MCRS1 at Human, Mouse |
| Immunogen: |
Synthesized peptide derived from human MCRS1 |
| Function | Modulates the transcription repressor activity of DAXX by recruiting it to the nucleolus. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. Putative regulatory component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. May also be an inhibitor of TERT telomerase activity. Binds to G-quadruplex structures in mRNA. Binds to RNA homomer poly(G) and poly(U). |
| Protein Name | Microspherule Protein 158 Kda Microspherule ProteinCell Cycle-Regulated Factor P78Ino80 Complex Subunit JMcrs2 |
| Database Links | Reactome: R-HSA-3214847Reactome: R-HSA-5689603Reactome: R-HSA-5696394Reactome: R-HSA-9772755 |
| Cellular Localisation | NucleusNucleolusCytoplasmIn Microspherules In The Nucleolus |
| Alternative Antibody Names | Anti-Microspherule Protein 1 antibodyAnti-58 Kda Microspherule Protein antibodyAnti-Cell Cycle-Regulated Factor P78 antibodyAnti-Ino80 Complex Subunit J antibodyAnti-Mcrs2 antibodyAnti-MCRS1 antibodyAnti-INO80Q antibodyAnti-MSP58 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
